Chlis, N.-K. ; Rausch, L.* ; Brocker, T.* ; Kranich, J.* & Theis, F.J.
Predicting single-cell gene expression profiles of imaging flow cytometry data with machine learning.
Nucleic Acids Res. 48, 11335-11346 (2020)
Zech, M. et al.
Monogenic variants in dystonia: An exome-wide sequencing study.
Lancet Neurol. 19, 908-918 (2020)
Benedetti, E. et al.
A strategy to incorporate prior knowledge into correlation network cutoff selection.
Nat. Commun. 11:5153 (2020)
Jagtap, P.K. et al.
Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
Nat. Commun. 11:5621 (2020)
Schoppe, O. et al.
Deep learning-enabled multi-organ segmentation in whole-body mouse scans.
Nat. Commun. 11 (2020)
Jiang, D. et al.
Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin.
Nat. Commun. 11 (2020)
Conlon, T.M. et al.
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
Nature, accepted (2020)
Kokot, H.* et al.
Prediction of chronic inflammation for inhaled particles: The impact of material cycling and quarantining in the lung epithelium.
Adv. Mater., accepted (2020)
Shnaiderman, R. et al.
A submicrometre silicon-on-insulator resonator for ultrasound detection.
Nature 585, 372-378 (2020)
Behr, J. et al.
Survival and course of lung function in the presence or absence of antifibrotic treatment in patients with idiopathic pulmonary fibrosis: Long-term results of the INSIGHTS-IPF registry.
Eur. Respir. J. 56:1902279 (2020)
Ignatova, V.V. et al.
METTL6 is a tRNA m3C methyltransferase that regulates pluripotency and tumor cell growth.
Sci. Adv. 6:eaaz4551 (2020)
Behr, J. et al.
Efficacy and safety of sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: A double-blind, randomised, placebo-controlled, phase 2b trial.
Lancet Resp. Med., accepted (2020)
Rydzek, S.* ; Shein, M.* ; Bielytskyi, P.* & Schütz, A.K.
Observation of a transient reaction intermediate illuminates the mechanochemical cycle of the AAA-ATPase p97.
J. Am. Chem. Soc. 142, 14472-14480 (2020)
Pittis, A.A.* et al.
Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter.
Nat. Commun. 11, 4031 (2020)
Haberer, G. et al.
European maize genomes highlight intraspecies variation in repeat and gene content.
Nat. Genet. 52, 950-957 (2020)
Walther, F. ; Hecker, N.* ; Stuckas, H.* & Hiller, M.*
Convergent losses of TLR5 suggest altered extracellular flagellin detection in four mammalian lineages.
Mol. Biol. Evol. 37, 1847-1854 (2020)
Strunz, M. et al.
Alveolar regeneration through a Krt8+transitional stem cell state that persists in human lung fibrosis.
Nat. Commun. 11:3559 (2020)
Bergen, V. ; Lange, M. ; Peidli, S.* ; Wolf, F.A.* & Theis, F.J.
Generalizing RNA velocity to transient cell states through dynamical modeling.
Nat. Biotechnol., accepted (2020)
Schriever, S.C. et al.
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
J. Clin. Invest. 130, 6093-6108 (2020)
Burton, A.* et al.
Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3.
Nat. Cell Biol. 22, 767-778 (2020)