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Fast deep-tissue multispectral optoacoustic tomography (MSOT) for preclinical imaging of cancer and cardiovascular disease.

In: Proceedings (SPIE Photons Plus Ultrasound: Imaging and Sensing 2012). Bellingham, USA: SPIE, 2012.:822302 (Proc. SPIE ; 8223)
Open Access Green as soon as Postprint is submitted to ZB.
Optoacoustic imaging has enabled the visualization of optical contrast at high resolutions in deep tissue. Our Multispectral optoacoustic tomography (MSOT) imaging results reveal internal tissue heterogeneity, where the underlying distribution of specific endogenous and exogenous sources of absorption can be resolved in detail. Technical advances in cardiac imaging allow motion-resolved multispectral measurements of the heart, opening the way for studies of cardiovascular disease. We further demonstrate the fast characterization of the pharmacokinetic profiles of lightabsorbing agents. Overall, our MSOT findings indicate new possibilities in high resolution imaging of functional and molecular parameters.
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Publication type Article: Conference contribution
Keywords Optoacoustic Imaging Small Animal Imaging ; Photoacoustic Imaging
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
ISBN 9780819488664
Conference Title SPIE Photons Plus Ultrasound: Imaging and Sensing 2012
Proceedings Title Proceedings
Quellenangaben Volume: 8223, Issue: , Pages: , Article Number: 822302 Supplement: ,
Series Proceedings of SPIE
Publisher SPIE
Publishing Place Bellingham, USA
Reviewing status Peer reviewed