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Mouse mutants as models for congenital retinal disorders.

Exp. Eye Res. 81, 503-512 (2005)
Verlagsversion DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Animal models provide a valuable tool for investigating the genetic basis and the pathophysiology of human diseases, and to evaluate therapeutic treatments. To study congenital retinal disorders, mouse mutants have become the most important model organism. Here we review some mouse models, which are related to hereditary disorders (mostly congenital) including retinitis pigmentosa, Leber's congenital amaurosis, macular disorders and optic atrophy.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter animal model; retina; mouse; gene mutation; retinal degeneration
ISSN (print) / ISBN 0014-4835
e-ISSN 1096-0007
Quellenangaben Band: 81, Heft: 5, Seiten: 503-512 Artikelnummer: , Supplement: ,
Verlag Elsevier
Begutachtungsstatus Peer reviewed