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Mourao, A.* ; Sattler, M.

Alternative splicing regulation: Structural and biophysical studies.

In: Encyclopedia of Biophysics. Berlin [u.a.]: Springer, 2013. 53-57
DOI Verlagsversion bestellen
Around 1980 it was discovered that protein variants of different size can be derived from the same gene. Later, it was shown that these alternative protein products result from differential inclusion of information from a given gene during pre-mRNA splicing. This process, called alternative splicing, entails, that pre-mRNA transcripts containing multiple exons can be spliced into different mRNAs and thus encode different proteins with distinct functions. A major consequence of alternative splicing is that the number of proteins in metazoan organisms greatly exceeds the number of genes.
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Publikationstyp Artikel: Sammelbandbeitrag/Buchkapitel
Herausgeber Roberts, G.C.K.*
Schlagwörter Alternative pre-mRNA splicing; Splicing
ISBN 978-3642167119
Bandtitel Encyclopedia of Biophysics
Quellenangaben Band: , Heft: , Seiten: 53-57 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort Berlin [u.a.]