PuSH - Publikationsserver des Helmholtz Zentrums München

Daniel, C.* ; Nolting, J.* ; von Boehmer, H.*

Mechanisms of self-nonself discrimination and possible clinical relevance.

Immunotherapy 1, 631-644 (2009)
PMC Verlagsversion bestellen
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
This review discusses different mechanisms that result in immunological tolerance, such as intrathymic deletion of immature T cells, intrathymic and extrathymic generation of regulatory T cells, effector mechanisms of regulatory T cells as well as molecular pathways involved in extrathymic generation of regulatory T cells in vivo and in vitro. These molecular mechanisms should enable investigators to develop clinical protocols aiming at the specific prevention of unwanted immune responses, thereby replacing indiscriminate immunosuppression that often has fatal consequences.
Altmetric
Weitere Metriken?
Zusatzinfos bearbeiten [➜Einloggen]
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
ISSN (print) / ISBN 1750-743X
e-ISSN 1750-7448
Zeitschrift Immunotherapy
Quellenangaben Band: 1, Heft: 4, Seiten: 631-644 Artikelnummer: , Supplement: ,
Verlag Future Medicine
Begutachtungsstatus