PuSH - Publication Server of Helmholtz Zentrum München

Degradation of glutathione S-conjugates by a carboxypeptidase in the plant vacuole.

FEBS Lett. 384, 31-34 (1996)
Open Access Green as soon as Postprint is submitted to ZB.
For plants, glutathione conjugation is a major pathway to detoxify organic xenobiotic. Glutathione S-conjugates (SG-conjugates) are formed in the cytosol, the in vitro transport over the tonoplast has been described and a final storage in the vacuole has been postulated. We show here that alachlor rapidly accumulates as GS-conjugates in the plant vacuole and that the first step of its degradation, the formation of the respective gamma-glutamylcysteinyl-S-conjugate, is catalyzed by a vacuolar carboxypeptidase, These results suggest the glutathione conjugate as a transport form but not a storage form of xenobiotic molecules.
Additional Metrics?
Edit extra informations Login
Publication type Article: Journal article
Document type Scientific Article
Keywords detoxification; glutathione conjugate; xenobiotic; carboxypeptidase; vacuole; METABOLISM
ISSN (print) / ISBN 0014-5793
e-ISSN 1873-3468
Journal FEBS Letters
Quellenangaben Volume: 384, Issue: 1, Pages: 31-34 Article Number: , Supplement: ,
Publisher Elsevier
Reviewing status Peer reviewed
Institute(s) Institute of Biochemical Plant Pathology (BIOP)
Abteilung Expositionskammern