Open Access Green as soon as Postprint is submitted to ZB.
Polymorphisms in extracellular signal-regulated kinase family influence genetic susceptibility to asthma.
J. Allergy Clin. Immunol. 131, 1245-1247 (2013)
Asthma susceptibility loci determined by genome-wide association studies explain only a fraction of asthma's hereditability. Pathway analysis has emerged as a next step toward mining hidden genetic factors in complex diseases. A recent study investigating the association between polymorphisms in Toll-like receptor signaling pathways and asthma revealed that 2 members of the mitogen-activated protein kinase (MAPK) pathway (MAP kinase kinase 3 and extracellular signal-regulated kinase 2 [ERK2]) showed strong association with the disease
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Publication type Article: Journal article
Document type Scientific Article
ISSN (print) / ISBN 0091-6749
Quellenangaben Volume: 131, Issue: 4, Pages: 1245-1247
Publishing Place Amsterdam [u.a.]
Reviewing status Peer reviewed
Institute(s) Research Unit Molecular Epidemiology (AME)