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Blood collection from mice and hematological analyses on mouse blood.
Curr. Protoc. Mouse Biol. 3, 101-119 (2013)
DOI
Basic phenotyping of inbred mouse strains and genetically modified mouse models usually includes the determination of blood-based parameters as a diagnostic screen for genotype effects on metabolism and organ function. A broad range of analytes, including hematological parameters, can be reliably determined in mouse blood, if appropriate samples are available. Here we describe recommended techniques for blood collection from mice and the considerations that have to be taken into account to get adequate samples for hematological investigations. Furthermore, we describe established methods used in the German Mouse Clinic (GMC) to determine hematological parameters in the mouse.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter mouse; blood sample collection; hematology
ISSN (print) / ISBN 2161-2617
Zeitschrift Current Protocols of Mouse Biology
Quellenangaben Band: 3, Heft: , Seiten: 101-119 Artikelnummer: , Supplement: ,
Verlag Wiley-Blackwell
Begutachtungsstatus peer-reviewed