PuSH - Publikationsserver des Helmholtz Zentrums München

Pfaff, J. ; Meister, G.*

Argonaute and GW182 proteins: An effective alliance in gene silencing.

Biochem. Soc. Trans. 41, 855-860 (2013)
Verlagsversion Volltext DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Argonaute proteins interact with small RNAs and facilitate small RNA-guided gene-silencing processes. Small RNAs guide Argonaute proteins to distinct target sites on mRNAs where Argonaute proteins interact with members of the GW182 protein family (also known as GW proteins). In subsequent steps, GW182 proteins mediate the downstream steps of gene silencing. The present mini-review summarizes and discusses our current knowledge of the molecular basis of Argonaute-GW182 protein interactions.
Altmetric
Weitere Metriken?
Zusatzinfos bearbeiten [➜Einloggen]
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Argonaute proteine; Gene silencing; GW182 protein; microRNA; miRNA; RNA interference; RNAi; Messenger-rna Degradation ; Crystal-structure ; Structural Basis ; Guide Rna ; Translational Repression ; Piwi-domain ; Paz Domain ; Human Ago2 ; Gw Bodies ; P-bodies
ISSN (print) / ISBN 0300-5127
e-ISSN 1470-8752
Quellenangaben Band: 41, Heft: 4, Seiten: 855-860 Artikelnummer: , Supplement: ,
Verlag Portland Press
Begutachtungsstatus Peer reviewed