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Sausenthaler, S. ; Loebel, T. ; Linseisen, J.* ; Nagel, G.* ; Magnussen, H.* ; Heinrich, J.

Vitamin E intake in relation to allergic sensitization and IgE serum concentration.

Cent. Eur. J. Public Health 17, 79-85 (2009)
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BACKGROUND: A protective role of dietary vitamin E intake on disorders related to the immune system, such as allergic diseases, has been suggested. However, results from epidemiological studies are conflicting. OBJECTIVES: The aim of present study was to analyze whether dietary vitamin E intake is related to the prevalence of allergic sensitization and total serum IgE concentrations in adult subjects. METHODS: The present study population consisted of 366 adults aged 29 to 54 years participating in the German centers of the European Community Respiratory Health Survey (ECRHS) II, Erfurt and Hamburg. A validated food frequency questionnaire was used to gather information on dietary vitamin E intake. Total serum IgE concentrations and specific IgE to common allergens were analyzed by using the Pharmacia CAP System. Allergic sensitization was defined as specific serum IgE concentration > or = 0.35 kU/l. RESULTS: The risk for allergic sensitization was substantially decreased in the middle quartiles (aOR: 0.42; 95% CI: 0.22-0.81) and the highest quartile (aOR: 0.22; 95% CI: 0.08-0.60) of total dietary vitamin E intake, after adjustment for potential confounders. Total serum IgE concentration was not statistically significantly associated with dietary vitamin E intake. CONCLUSIONS: The findings of this study suggest that dietary vitamin E intake might play a protective role in the development of allergic sensitization.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Adults ; Allergic sensitization ; α-tocopherol ; Dietary vitamin E ; ECRHS II; Immunoglobulin E
ISSN (print) / ISBN 1210-7778
e-ISSN 1803-1048
Quellenangaben Band: 17, Heft: 2, Seiten: 79-85 Artikelnummer: , Supplement: ,
Verlag National Institute of Public Health
Verlagsort Prag
Begutachtungsstatus Peer reviewed