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Imaging the small animal cardiovascular system in real-time with multispectral optoacoustic tomography.

Proc. SPIE 7899:789913 (2011)
Publ. Version/Full Text DOI
Open Access Green as soon as Postprint is submitted to ZB.
Multispectral Optoacoustic Tomography (MSOT) is an emerging technique for high resolution macroscopic imaging with optical and molecular contrast. We present cardiovascular imaging results from a multi-element real-time MSOT system recently developed for studies on small animals. Anatomical features relevant to cardiovascular disease, such as the carotid arteries, the aorta and the heart, are imaged in mice. The system's fast acquisition time, in tens of microseconds, allows images free of motion artifacts from heartbeat and respiration. Additionally, we present in-vivo detection of optical imaging agents, gold nanorods, at high spatial and temporal resolution, paving the way for molecular imaging applications.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Molecular Imaging ; Optical Imaging ; Optoacoustic Tomography ; Photoacoustic Imaging ; Small Animal Imaging
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Conference Title Photons Plus Ultrasound: Imaging and Sensing 2011
Conference Date January 22, 2011
Conference Location San Francisco, California, USA
Quellenangaben Volume: 7899, Issue: , Pages: , Article Number: 789913 Supplement: ,
Publisher SPIE
Reviewing status Peer reviewed