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Eichner, J.* ; Rosenbaum, L.* ; Wrzodek, C.* ; Häring, H.-U. ; Zell, A.* ; Lehmann, R.

Integrated enrichment analysis and pathway-centered visualization of metabolomics, proteomics, transcriptomics, and genomics data by using the InCroMAP software.

J. Chromatogr. B 966, 77-82 (2014)
Open Access Green as soon as Postprint is submitted to ZB.
In systems biology, the combination of multiple types of omics data, such as metabolomics, proteomics, transcriptomics, and genomics, yields more information on a biological process than the analysis of a single type of data. Thus, data from different omics platforms is usually combined in one experimental setup to obtain insight into a biological process or a disease state. Particularly high accuracy metabolomics data from modern mass spectrometry instruments is currently more and more integrated into biological studies. Reflecting this trend, we extended InCroMAP, a data integration, analysis and visualization tool for genomics, transcriptomics, and proteomics data. Now, the tool is able to perform an integrated enrichment analysis and pathway-based visualization of multi-omics data and thus, it is suitable for the evaluation of comprehensive systems biology studies.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Enrichment Analysis ; Genomics ; Metabolomics ; Pathway Visualization ; Proteomics ; Transcriptomics; Web-based Tool; Knowledgebase
ISSN (print) / ISBN 1570-0232
e-ISSN 1873-376X
Quellenangaben Volume: 966, Issue: , Pages: 77-82 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Amsterdam
Reviewing status Peer reviewed