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Omar, M. ; Soliman, D. ; Gateau, J.* ; Ntziachristos, V.

Ultrawideband reflection-mode optoacoustic mesoscopy.

Opt. Lett. 39, 3911-3914 (2014)
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
We developed a reflection-mode optoacoustic mesoscopy system, based on raster-scanning of a custom designed spherically focused ultrasound detector, enabling seamless epi-illumination of the volume imaged. We study the performance of acoustic-resolution mesoscopy operating at an ultrawideband bandwidth of 20–180 MHz. i.e., a frequency band spreading over virtually an order of magnitude. Using tomographic reconstruction we showcase previously unreported, to our knowledge, axial resolutions of 4 μm and transverse resolutions of 18 μm reaching depths of up to 5 mm. We further investigate the frequency-dependence of features seen on the images to understand the implications of ultrawideband measurements. We show the overall imaging performance and the frequency ranges that contribute to observable resolution improvements from phantoms and animals.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Photoacoustic Microscopy; Resolution
ISSN (print) / ISBN 0146-9592
e-ISSN 1539-4794
Zeitschrift Optics Letters
Quellenangaben Band: 39, Heft: 13, Seiten: 3911-3914 Artikelnummer: , Supplement: ,
Verlag Optical Society of America (OSA)
Verlagsort Washington
Begutachtungsstatus Peer reviewed