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Zeiser, S. ; Franz, U.* ; Wittich, O.* ; Liebscher, V.*

Simulation of genetic networks modelled by piecewise deterministic Markov processes.

IET Syst. Biol. 2, 113-135 (2008)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
The authors propose piecewise deterministic Markov processes as an alternative approach to model gene regulatory networks. A hybrid simulation algorithm is presented and discussed, and several standard regulatory modules are analysed by numerical means. It is shown that despite of the partial simplification of the mesoscopic nature of regulatory networks such processes are suitable to reveal the intrinsic noise effects because of the low copy numbers of genes.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
ISSN (print) / ISBN 1751-8849
e-ISSN 1751-8857
Zeitschrift IET Systems Biology
Quellenangaben Band: 2, Heft: 3, Seiten: 113-135 Artikelnummer: , Supplement: ,
Verlag Institution of Engineering and Technology (IET)
Begutachtungsstatus Peer reviewed