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Simulation of genetic networks modelled by piecewise deterministic Markov processes.
IET Syst. Biol. 2, 113-135 (2008)
The authors propose piecewise deterministic Markov processes as an alternative approach to model gene regulatory networks. A hybrid simulation algorithm is presented and discussed, and several standard regulatory modules are analysed by numerical means. It is shown that despite of the partial simplification of the mesoscopic nature of regulatory networks such processes are suitable to reveal the intrinsic noise effects because of the low copy numbers of genes.
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Publication type Article: Journal article
Document type Scientific Article
ISSN (print) / ISBN 1751-8849
Journal IET Systems Biology
Quellenangaben Volume: 2, Issue: 3, Pages: 113-135
Publisher Institution of Engineering and Technology (IET)
Reviewing status Peer reviewed
Institute(s) Institute of Biomathematics and Biometry (IBB)