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Scientific basis for aerosol therapy using nebulizers.

Eur. Respir. Rev. 4, 95-98 (1994)
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Important properties of nebulizers for aerosol particle therapy are the water and solute output, and the initial particle size distribution. These properties have to be determined experimentally. The evaporation of the particles during transport is estimated to be less than 10% in most cases. The changes in particle size during inhalation, and particle deposition, are estimated with a hygroscopic particle lung deposition model. The regional deposition of aerosol particles of an arbitrary material and an arbitrary size distribution can now be estimated. This method is applied to two jet nebulizers (Pari Inhalierboy and Wiesbadener Doppelinhalator), and to an ultrasonic nebulizer (DeVilbiss 65).
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Publication type Article: Journal article
Document type Scientific Article
ISSN (print) / ISBN 0905-9180
e-ISSN 1600-0617
Quellenangaben Volume: 4, Issue: 18, Pages: 95-98 Article Number: , Supplement: ,
Publisher European Respiratory Society
Reviewing status Peer reviewed
Institute(s) Institut für Inhalationsbiologie (IHB)