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Genes on B chromosomes: Old questions revisited with new tools.
Biochim. Biophys. Acta-Gene Regul. Mech. 1849, 64-70 (2014)
B chromosomes are supernumerary dispensable parts of the karyotype which appear in some individuals of some populations in some species. Often, they have been considered as 'junk DNA' or genomic parasites without functional genes. Due to recent advances in sequencing technologies, it became possible to investigate their DNA composition, transcriptional activity and effects on the host transcriptome profile in detail. Here, we review the most recent findings regarding the gene content of B chromosomes and their transcriptional activities and discuss these findings in the context of comparable biological phenomena, like sex chromosomes, aneuploidy and pseudogenes.
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Publication type Article: Journal article
Document type Review
Keywords Gene Regulation ; Genome Evolution ; Junk Dna ; Pseudogene ; Supernumerary Chromosome ; Transcription; Grasshopper Eyprepocnemis-plorans; H3 Methylation Marks; Histone H3; Brachycome-dichromosomatica; Sex-chromosomes; Supernumerary Chromosome; Centromeric Drive; Dna Methylation; Reduced Level; Ribosomal-rna