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Coskun, Ü.* ; Simons, K.*

Cell membranes: The lipid perspective.

Structure 19, 1543-1548 (2011)
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Although cell membranes are packed with proteins mingling with lipids, remarkably little is known about how proteins interact with lipids to carry out their function. Novel analytical tools are revealing the astounding diversity of lipids in membranes. The issue is now to understand the cellular functions of this complexity. In this Perspective, we focus on the interface of integral transmembrane proteins and membrane lipids in eukaryotic cells. Clarifying how proteins and lipids interact with each other will be important for unraveling membrane protein structure and function. Progress toward this goal will be promoted by increasing overlap between different fields that have so far operated without much crosstalk.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
ISSN (print) / ISBN 0969-2126
e-ISSN 1878-4186
Zeitschrift Structure
Quellenangaben Band: 19, Heft: 11, Seiten: 1543-1548 Artikelnummer: , Supplement: ,
Verlag Cell Press
Begutachtungsstatus
Institut(e) Institute for Pancreatic Beta Cell Research (IPI)