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Omar, M. ; Soliman, D. ; Gateau, J.* ; Ntziachristos, V.

Retrieving small features in reflection-mode Raster-Scan Optoacoustic Mesoscopy (RSOM) using multi-frequency reconstruction.

Proc. SPIE 9323:932326 (2015)
Verlagsversion DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
We developed a reflection-mode, raster-scan optoacoustic mesoscopy system, based on a custom-made ultrasonic detector, with an ultra wide bandwidth of 20-180 MHz. To optimally use this bandwidth, we implemented multi-frequency reconstruction. System characterization reveals a 4 μm axial, and 18 μm transverse resolution, at penetration depths reaching 5 mm. After characterization, the system was applied to image a zebrafish ex vivo, and an excised mouse ear. In the zebrafish, the lateral line, intestines, eyes, and melanocytes are seen, while in the mouse ear, multi-frequency reconstruction recovered the small vessels, otherwise not seen on the image.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Beam-forming ; Epi-illumination ; High Frequency ; Mesoscopy ; Microscopy ; Optoacoustics
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Konferenztitel Photons Plus Ultrasound Imaging and Sensing 2015
Konferzenzdatum 8.-10. February 2015
Konferenzort San Francisco, USA
Zeitschrift Proceedings of SPIE
Quellenangaben Band: 9323, Heft: , Seiten: , Artikelnummer: 932326 Supplement: ,
Verlag SPIE
Begutachtungsstatus Peer reviewed