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Epidemiology of air pollution and diabetes.

Trends Endocrinol. Metab. 26, 384-394 (2015)
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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Air pollution affects a large proportion of the global population. Air pollutants are hypothesized to exert their effects via impaired endothelial function, elevated systemic inflammation, mitochondrial dysfunction, and oxidative stress, all of which are hallmarks of type 2 diabetes (T2D). Here we review epidemiological studies aimed at answering whether diabetes patients are more vulnerable to ambient (outdoor) air pollution exposure and whether air pollution is associated with diabetes development or other predisposing conditions for T2D. Current evidence suggests an association between air pollution exposure and T2D, but more critical analysis is warranted. Understanding the associations between air pollution exposure and the development of T2D is critical in our efforts to control sources of air pollution and their impact on the disease.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Air Pollution ; Gestational Diabetes ; Mortality ; Type 2 Diabetes; Long-term Exposure; Fine Particulate Matter; Case-crossover Analysis; Insulin-resistance; Daily Mortality; Risk-factors; Cardiovascular-disease; Susceptibility Factors; Effect Modifiers; Lung-cancer
ISSN (print) / ISBN 1043-2760
e-ISSN 1879-3061
Quellenangaben Band: 26, Heft: 7, Seiten: 384-394 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort London
Begutachtungsstatus Peer reviewed