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Blood monocytes and their subsets: Established features and open questions.

Front. Immunol. 6:423 (2015)
Verlagsversion DOI
Open Access Gold
Creative Commons Lizenzvertrag
In contrast to the past reliance on morphology, the identification and enumeration of blood monocytes are nowadays done with monoclonal antibodies and flow cytometry and this allows for subdivision into classical, intermediate, and non-classical monocytes. Using specific cell surface markers, dendritic cells in blood can be segregated from these monocytes. While in the past, changes in monocyte numbers as determined in standard hematology counters have not had any relevant clinical impact, the subset analysis now has uncovered informative changes that may be used in management of disease.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Classical Monocytes ; Intermediate Monocytes ; Monocyte Subsets ; Nomenclature ; Non-classical Monocytes; Human Peripheral-blood; Human Dendritic Cells; Predict Cardiovascular Events; Cd14(+) Cd16(+) Monocytes; Gene-expression Profiles; Chronic Kidney-disease; Fc-epsilon-ri; Bone-marrow; Cd16-positive Monocytes; M-dc8(+) Monocytes
ISSN (print) / ISBN 1664-3224
e-ISSN 1664-3224
Quellenangaben Band: 6, Heft: , Seiten: , Artikelnummer: 423 Supplement: ,
Verlag Frontiers
Verlagsort Lausanne
Begutachtungsstatus Peer reviewed