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Five-dimensional optoacoustic tomography for real-time whole brain neuroimaging of stimulus-evoked responses.
In: (7th International IEEE/EMBS Conference on Neural Engineering (NER), 2015, 22-24 April 2015). 2015.
We present a technique for fully noninvasive acquisition of real-time volumetric multispectral optoacoustic data from whole mouse brain. The neuroimaging capacity of the new methodology is demonstrated here by simultaneous label-free assessment of multiple stimulus-evoked hemodynamic responses, including blood oxygenation, total hemoglobin, cerebral blood volume, oxygenized and deoxygenized hemoglobin.
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Publication type Article: Conference contribution
Keywords Blood, Real-time systems, Hemodynamics, Mice, Neuroimaging, Veins, Tomography
Conference Title 7th International IEEE/EMBS Conference on Neural Engineering (NER), 2015
Conference Date 22-24 April 2015
Institute(s) Institute of Biological and Medical Imaging (IBMI)