PuSH - Publikationsserver des Helmholtz Zentrums München

Spella, M.* ; Marazioti, A.* ; Arendt, K.A.M. ; Stathopoulos, G.T.

RAS oncogenes direct metastasis.

Mol. Cell. Oncol. 4:e1345711 (2017)
DOI PMC Verlagsversion bestellen
RAS genes are cardinal driver oncogenes frequently and differentially mutated across bodily tumors. Their tumorigenic potential has been mainly ascribed to autonomous promotion of tumor cell proliferation and survival. However, recent evidence shows that RAS oncogenes also function to define metastatic tropism. Interestingly, RAS-driven metastasis is mediated by distinct chemokine sets that signal to endothelial and myeloid cells.
Altmetric
Weitere Metriken?
Zusatzinfos bearbeiten [➜Einloggen]
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Chemokines ; Kras ; Lung Metastasis ; Malignant Pleural Effusion ; Nras
e-ISSN 2372-3556
Zeitschrift Molecular & Cellular Oncology
Quellenangaben Band: 4, Heft: 5, Seiten: , Artikelnummer: e1345711 Supplement: ,
Verlag Taylor & Francis
Begutachtungsstatus