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NeuBtracker-imaging neurobehavioral dynamics in freely behaving fish.
Nat. Methods 14, 1079-1082 (2017)
A long-standing objective in neuroscience has been to image distributed neuronal activity in freely behaving animals. Here we introduce NeuBtracker, a tracking microscope for simultaneous imaging of neuronal activity and behavior of freely swimming fluorescent reporter fish. We showcase the value of NeuBtracker for screening neurostimulants with respect to their combined neuronal and behavioral effects and for determining spontaneous and stimulus-induced spatiotemporal patterns of neuronal activation during naturalistic behavior.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Light-sheet Microscopy; Brain Activity; Embryonic-development; Neuronal-activity; Larval Zebrafish; Neural Activity; Perception; Receptor
ISSN (print) / ISBN 1548-7091
Journal Nature Methods
Quellenangaben Volume: 14, Issue: 11, Pages: 1079-1082
Publisher Nature Publishing Group
Publishing Place New York, NY
Reviewing status Peer reviewed