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Ertl, M.* ; Raasch, N.* ; Hammel, G. ; Zeiser, K. ; Lang, C.*

Transtemporal investigation of brain parenchyma elasticity using 2-D shear wave elastography: Definition of age-matched normal values.

Ultrasound Med. Biol. 44, 78-84 (2017)
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The goal of our research was to assess the possibility of reliable investigation of brain tissue stiffness using ultrasonographic brain parenchyma elastography with an intact temporal bone. We enrolled 108 patients after exclusion of intracranial pathology or healthy volunteers. All patients were subdivided by age into groups: 20-40, 40-60 and >60 y. For statistical analysis, the χ(2) test and t-test were used. The mean values, regardless of age and other parameters, were 3.34 kPa (SD = 0.59) on the left side and 3.33 kPa (SD = 0.58) on the right side. We found no correlation between the values, body mass index (r = 0.07, p = 0.48) and sex (t = -0.11, p = 0.91), but we observed a highly significant correlation between the values and age (r = 0.43, p <0.0001). We found ultrasonographic brain parenchyma elastography to be a valid, reproducible and investigator-independent method that reliably determines brain parenchyma stiffness. Normal values should serve as a reference for studies on various intracranial lesions.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter 2-d- Shear Wave Elastography ; Brain Elastography ; Stroke ; Transtemporal Ultrasound; 1 Basic Principles; Clinical-use; Wfumb Guidelines; Neonatal Brain; Recommendations; Breast; Stiffness; Stroke
ISSN (print) / ISBN 0301-5629
e-ISSN 1879-291X
Quellenangaben Band: 44, Heft: 1, Seiten: 78-84 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort New York
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Environmental Medicine (IEM)