Open Access Green as soon as Postprint is submitted to ZB.
The phenomenology of cell size control.
Curr. Opin. Cell Biol. 49, 53-58 (2017)
Cells control their size through an intricate balance of cell growth, cell division, and cell death. Extensive work on unicellular model organisms revealed that cell-size-dependent cell cycle progression accounts for major aspects of cell size regulation and provided insights into the underlying molecular mechanisms. Nevertheless, elaborate live-cell imaging approaches still reveal new phenomenological observations that challenge our simplified models of size regulation and raise the question of what determines optimal cell size. Here, I aim to give a conceptual overview of the many processes contributing to cell size regulation and summarize recent developments in the field.
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Publication type Article: Journal article
Document type Review
Keywords Fission Yeast; Budding-yeast; Escherichia-coli; Division Cycle; Growth; Homeostasis; Replication; Competition; Reveals; Volume
ISSN (print) / ISBN 0955-0674
Journal Current Opinion in Cell Biology
Quellenangaben Volume: 49, Pages: 53-58
Publishing Place Kidlington
Reviewing status Peer reviewed
Institute(s) Institute of Functional Epigenetics (IFE)