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The phenomenology of cell size control.

Curr. Opin. Cell Biol. 49, 53-58 (2017)
Publ. Version/Full Text DOI
Open Access Green as soon as Postprint is submitted to ZB.
Cells control their size through an intricate balance of cell growth, cell division, and cell death. Extensive work on unicellular model organisms revealed that cell-size-dependent cell cycle progression accounts for major aspects of cell size regulation and provided insights into the underlying molecular mechanisms. Nevertheless, elaborate live-cell imaging approaches still reveal new phenomenological observations that challenge our simplified models of size regulation and raise the question of what determines optimal cell size. Here, I aim to give a conceptual overview of the many processes contributing to cell size regulation and summarize recent developments in the field.
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Publication type Article: Journal article
Document type Review
Keywords Fission Yeast; Budding-yeast; Escherichia-coli; Division Cycle; Growth; Homeostasis; Replication; Competition; Reveals; Volume
ISSN (print) / ISBN 0955-0674
e-ISSN 1879-0410
Quellenangaben Volume: 49, Issue: , Pages: 53-58 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Kidlington
Reviewing status Peer reviewed