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COPD patients as vulnerable subpopulation for exposure to ambient air pollution.
Curr. Environ. Health Rep., DOI: 10.1007/s40572-018-0178-z (2018)
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PURPOSE OF REVIEW: The prevalence of chronic obstructive pulmonary disease (COPD) is increasing worldwide with no known cure and an increasing number of triggers that exacerbate symptoms and speed up progression. This review aims to summarize the evidence for COPD patients being more vulnerable to air pollution exposure assessed as acute effects. RECENT FINDINGS: Several recent systematic reviews show consistently increased risks for COPD mortality and COPD hospital admission, ranging between 2 and 3% with increasing PMor PM. Similar adverse impacts were shown for NOAlsoadverse health effects among COPD patients were also found for other gaseous pollutants such as ozone and SO; most of these studies could not be included in the meta-analysis we reviewed. Data from ten panel studies of COPD patients reported a small but statistically significant decline of FEV1 [- 3.38 mL (95% CI - 6.39 to - 0.37)] per increment of 10 μg/m PM, supporting an impact on respiratory health with increasing PMexposure. The combined information from systematic reviews and more recent findings lead us to conclude that COPD patients are more vulnerable to ambient air pollution than healthier people.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Ambient Air Pollution ; Co ; Copd ; Copd Exacerbation ; No2 ; Ozone ; Pm2.5 ; So2 ; Vulnerability
ISSN (print) / ISBN 2196-5412
Zeitschrift Current environmental health reports
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology I (EPI1)