PuSH - Publikationsserver des Helmholtz Zentrums München

Meiners, S. ; Evankovich, J.* ; Mallampalli, R.K.*

The ubiquitin proteasome system as a potential therapeutic target for systemic sclerosis.

Transl. Res., DOI: 10.1016/j.trsl.2018.03.003 (2018)
Postprint DOI Verlagsversion bestellen
Open Access Green
The present review aims to summarize available knowledge on the role of the ubiquitin-proteasome system (UPS) in the pathogenesis of scleroderma and scleroderma-related disease mechanisms. This will provide the reader with a more mechanistic understanding of disease pathogenesis and help to identify putative novel targets within the UPS for potential therapeutic intervention. Because of the heterogenous manifestations of scleroderma, we will primarily focus on conserved mechanisms that are involved in the development of lung scleroderma phenotypes.
Weitere Metriken?
Zusatzinfos bearbeiten [➜Einloggen]
Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
ISSN (print) / ISBN 1931-5244
e-ISSN 1878-1810
Verlag Elsevier
Verlagsort New York, NY
Begutachtungsstatus Peer reviewed