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Kyriakou, E. ; Kostagianni, A.D.* ; Kellici, T.F.* ; Giannopoulou, E.A.* ; Siatis, K.E.* ; Sayyad, N.* ; Kalofonos, H.P.* ; Mavromoustakos, T.* ; Stamatis, H.* ; Tzakos, A.G.*

Three regioselectively acylated flavonoid aglycone derivatives in equimolar yield at one blow.

ChemistrySelect 3, 5207-5211 (2018)
Verlagsversion Postprint DOI
Open Access Green
A simple and time‐effective chemoenzymatic process to obtain three regioselective acylated quercetin analogues in a 1:1:1 ratio in one pot is described. This process overcomes the inherent scaffold intricacy and synthetic complexity of quercetin. Cell proliferation experiments in three breast cancers cell lines pinpoint the high potency of the generated compounds.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Biocatalysis ; Cancer ; Quercetin ; In Silico Studies ; Nmr Experiments ; Regioselectivity
ISSN (print) / ISBN 2365-6549
e-ISSN 2365-6549
Zeitschrift ChemistrySelect
Quellenangaben Band: 3, Heft: 18, Seiten: 5207-5211 Artikelnummer: , Supplement: ,
Verlag Wiley
Verlagsort Weinheim
Begutachtungsstatus Peer reviewed