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The transcriptional landscape of polyploid wheat.

Science 361 (2018)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
The coordinated expression of highly related homoeologous genes in polyploid species underlies the phenotypes of many of the world's major crops. Here we combine extensive gene expression datasets to produce a comprehensive, genome-wide analysis of homoeolog expression patterns in hexaploid bread wheat. Bias in homoeolog expression varies between tissues, with similar to 30% of wheat homoeologs showing nonbalanced expression. We found expression asymmetries along wheat chromosomes, with homoeologs showing the largest inter-tissue, inter-cultivar, and coding sequence variation, most often located in high-recombination distal ends of chromosomes. These transcriptionally dynamic genes potentially represent the first steps toward neo- or subfunctionalization of wheat homoeologs. Coexpression networks reveal extensive coordination of homoeologs throughout development and, alongside a detailed expression atlas, provide a framework to target candidate genes underpinning agronomic traits in wheat.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Whole-genome Duplication; Body Dna Methylation; Gene-expression; Plants; Evolution; Arabidopsis; Domestication; Divergence; Resistance; Dominance
Reviewing status