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Rauser, S. ; Deininger, S.O.* ; Suckau, D.* ; Höfler, H. ; Walch, A.K.

Approaching MALDI molecular imaging for clinical proteomic research: Current state and fields of application.

Expert Rev. Proteomics 7, 927-941 (2010)
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Open Access Green
MALDI imaging mass spectrometry ('MALDI imaging') is an increasingly recognized technique for biomarker research. After years of method development in the scientific community, the technique is now increasingly applied in clinical research. In this article, we discuss the use of MALDI imaging in clinical proteomics and put it in context with classical proteomics techniques. We also highlight a number of upcoming challenges for personalized medicine, development of targeted therapies and diagnostic molecular pathology where MALDI imaging could help.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter biomarker discovery; clinical proteomics; MALDI imaging; MALDI imaging mass spectrometry; molecular pathology; personalized medicine; tissue analysis
ISSN (print) / ISBN 1478-9450
e-ISSN 1744-8387
Zeitschrift Expert Review of Proteomics
Quellenangaben Band: 7, Heft: 6, Seiten: 927-941 Artikelnummer: , Supplement: ,
Verlag Expert Reviews
Begutachtungsstatus