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Singh, H.R.* ; Stricker, S.H.

Glucose-regulated TET2 activity links cancer to diabetes.

Trends Cancer 5, 5-7 (2019)
Postprint DOI Order publishers version
Open Access Green
Diabetes has long been associated with an increased risk of cancer. While many molecular connections likely exist between the diseases, a recent publication discovered a clear molecular link, demonstrating that a glucose-dependent destabilisation of the DNA demethylase TET2 can promote-malignant transformation via an AMPK-dependent phosphoswitch.
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Publication type Article: Journal article
Document type Review
Keywords Dna Methylation
ISSN (print) / ISBN 2405-8033
e-ISSN 2405-8025
Quellenangaben Volume: 5, Issue: 1, Pages: 5-7 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Amsterdam
Reviewing status Peer reviewed