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Lamort, A.-S. ; Giopanou, I.* ; Psallidas, I.* ; Stathopoulos, G.T.

Osteopontin as a link between inflammation and cancer: The thorax in the spotlight.

Cells 8:815 (2019)
Verlagsversion DOI
Open Access Gold
Creative Commons Lizenzvertrag
The glycoprotein osteopontin (OPN) possesses multiple functions in health and disease. To this end, osteopontin has beneficial roles in wound healing, bone homeostasis, and extracellular matrix (ECM) function. On the contrary, osteopontin can be deleterious for the human body during disease. Indeed, osteopontin is a cardinal mediator of tumor-associated inflammation and facilitates metastasis. The purpose of this review is to highlight the importance of osteopontin in malignant processes, focusing on lung and pleural tumors as examples.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Opn ; Spp1 ; Inflammation ; Lung Cancer ; Secreted Phosphoprotein 1
ISSN (print) / ISBN 2073-4409
e-ISSN 2073-4409
Zeitschrift Cells
Quellenangaben Band: 8, Heft: 8, Seiten: , Artikelnummer: 815 Supplement: ,
Verlag MDPI
Verlagsort Basel