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Roux, F.* ; Colomé-Tatché, M. ; Edelist, C.* ; Wardenaar, R.* ; Guerche, P.* ; Hospital, F.* ; Colot, V.* ; Jansen, R.C.* ; Johannes, F.*

Genome-wide epigenetic perturbation jump-starts patterns of heritable variation found in nature.

Genetics 188, 1015-1017 (2011)
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We extensively phenotyped 6000 Arabidopsis plants with experimentally perturbed DNA methylomes as well as a diverse panel of natural accessions in a common garden. We found that alterations in DNA methylation not only caused heritable phenotypic diversity but also produced heritability patterns closely resembling those of the natural accessions. Our findings indicate that epigenetically induced and naturally occurring variation in complex traits share part of their polygenic architecture and may offer complementary adaptation routes in ecological settings.
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Publication type Article: Journal article
Document type Other: Opinion
ISSN (print) / ISBN 0016-6731
e-ISSN 0016-6731
Journal Genetics
Quellenangaben Volume: 188, Issue: 4, Pages: 1015-1017 Article Number: , Supplement: ,
Publisher Genetics Society of America
Reviewing status Peer reviewed