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Nimptsch, K.* ; Jaeschke, L.* ; Chang-Claude, J.* ; Kaaks, R.* ; Katzke, V.* ; Michels, K.B.* ; Franzke, C.W.* ; Obi, N.* ; Becher, H.* ; Kuß, O.* ; Schikowski, T.* ; Schulze, M.B.* ; Gastell, S.* ; Hoffmann, W.* ; Schipf, S.* ; Ahrens, W.* ; Günther, K.* ; Krist, L.* ; Keil, T.* ; Jöckel, K.H.* ; Schmidt, B.* ; Brenner, H.* ; Holleczek, B.* ; Fischer, B.* ; Leitzmann, M.* ; Lieb, W.* ; Berger, K.* ; Krause, G.* ; Löffler, M.* ; Schmidt-Pokrzywniak, A.* ; Mikolajczyk, R.* ; Linseisen, J. ; Greiser, K.H.* ; Pischon, T.*

Self-reported cancer in the German National Cohort (NAKO Gesundheitsstudie): Assessment methods and first results.

Self-reported cancer in the German National Cohort (NAKO Gesundheitsstudie): Assessment methods and first results.

Bundesgesundheitsbl.-Gesund. 63, 385-396 (2020)
Publ. Version/Full Text DOI
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Background: In the German National Cohort (NAKO Gesundheitsstudie), the largest prospective cohort study in Germany, data on self-reported cancer diagnoses are now available for the first half of participants. Objectives: Description of the methods to assess self-reported cancer diagnoses and type of cancer in the NAKO and presentation of first results. Materials and methods: In a computer-assisted, standardized personal interview, 101,787 participants (54,526 women, 47,261 men) were asked whether they had ever been diagnosed with cancer (malignant tumors including in situ) by a physician and how many cancer diagnoses they had. The type of cancer was classified with a list. Absolute and relative frequencies of self-reported cancer diagnoses and types of cancer were calculated and compared with cancer registry data. Results: A physician-diagnosed cancer was reported by 9.4% of women and 7.0% of men. Of the participants who reported a cancer diagnosis, 88.3% reported to have had only one cancer diagnosis. In women, the most frequent malignancies were breast cancer, cervical cancer, and melanoma. In men, the most frequent malignancies were prostate cancer, melanoma, and colorectal cancer. Comparing the frequencies of cancer diagnoses reported by 45- to 74-year-old NAKO participants within the last five years to cancer registry-based 5‑year prevalences, most types of cancer were less frequent in the NAKO, with the exception of melanoma in men and women, cervical cancer and liver cancer in women, and bladder cancer and breast cancer in men. Conclusions: The NAKO is a rich data basis for future investigations of incident cancer.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Cancer ; Cohort Study ; Epidemiology ; Germany ; Self-report; Volunteer; Recruitment; Prevalence
ISSN (print) / ISBN 1436-9990
e-ISSN 1437-1588
Quellenangaben Volume: 63, Issue: 4, Pages: 385-396 Article Number: , Supplement: ,
Publisher Springer
Publishing Place One New York Plaza, Suite 4600, New York, Ny, United States
Reviewing status Peer reviewed