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Bernhardt, D. ; Wick, W.* ; Weiss, S.E.* ; Sahgal, A.* ; Lo, S.S.* ; Suh, J.H.* ; Chang, E.L.* ; Foote, M.* ; Perry, J.* ; Meyer, B.* ; Vajkoczy, P.* ; Wen, P.Y.* ; Straube, C. ; Pigorsch, S.U. ; Wilkens, J.J.* ; Combs, S.E.

Neuro-oncology managment during the COVID-19 pandemic with a focus on WHO grade III and IV gliomas.

Neuro. Oncol. 22, 928-935 (2020)
Publ. Version/Full Text Postprint DOI
Open Access Green
BACKGROUND: Because of the increased risk in cancer patients of developing complications caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), physicians have to balance the competing risks of the negative impact of the pandemic and the primary tumor. In this consensus statement, an international group of experts present mitigation strategies and treatment guidance for patients suffering from high grade gliomas (HGG) during the coronavirus disease 2019 (COVID-19) pandemic. METHOD / RESULTS: 16 international experts in the treatment of HGG contributed to this consensus-based practice recommendation including neuro-oncologists, neurosurgeons, radiation -oncologists and a medical physicist. Generally, treatment of neuro-oncological patients cannot be significantly delayed and initiating therapy should not be outweighed by COVID-19. We present detailed interdisciplinary treatment strategies for molecular subgroups in two pandemic scenarios, a scale-up phase and a crisis phase. CONCLUSION: This practice recommendation presents a pragmatic framework and consensus-based mitigation strategies for the treatment of HGG patients during the SARS-CoV-2 pandemic.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Covid-19 ; Sars-cov-2 ; Glioblastoma ; High-grade Glioma ; Neuro-oncology; Newly-diagnosed Glioblastoma; Radiation-therapy; Older Patients; Temozolomide; Radiotherapy; Multiforme; Survival
ISSN (print) / ISBN 1522-8517
e-ISSN 1523-5866
Journal Neuro-Oncology
Quellenangaben Volume: 22, Issue: 7, Pages: 928-935 Article Number: , Supplement: ,
Publisher Oxford University Press
Publishing Place Journals Dept, 2001 Evans Rd, Cary, Nc 27513 Usa
Reviewing status Peer reviewed