PuSH - Publikationsserver des Helmholtz Zentrums München

Gabashvili, A.N.* ; Chmelyuk, N.S.* ; Efremova, M.V. ; Malinovskaya, J.A.* ; Semkina, A.S.* ; Abakumov, M.A.*

Encapsulins-bacterial protein nanocompartments: Structure, properties, and application.

Biomolecules 10:966 (2020)
Verlagsversion DOI
Open Access Gold
Creative Commons Lizenzvertrag
Recently, a new class of prokaryotic compartments, collectively called encapsulins or protein nanocompartments, has been discovered. The shell proteins of these structures self-organize to form icosahedral compartments with a diameter of 25-42 nm, while one or more cargo proteins with various functions can be encapsulated in the nanocompartment. Non-native cargo proteins can be loaded into nanocompartments and the surface of the shells can be further functionalized, which allows for developing targeted drug delivery systems or using encapsulins as contrast agents for magnetic resonance imaging. Since the genes encoding encapsulins can be integrated into the cell genome, encapsulins are attractive for investigation in various scientific fields, including biomedicine and nanotechnology.
Altmetric
Weitere Metriken?
Zusatzinfos bearbeiten [➜Einloggen]
Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Encapsulin ; Nanocompartment ; Cell Labeling ; Mri; Rhodococcus-jostii Rha1; Mycobacterium-tuberculosis; In-vitro; Iron Storage; Virus; Delivery; Identification; Nanoparticles; Ferritin; Esha
ISSN (print) / ISBN 2218-273X
e-ISSN 2218-273X
Zeitschrift Biomolecules
Quellenangaben Band: 10, Heft: 6, Seiten: , Artikelnummer: 966 Supplement: ,
Verlag MDPI
Verlagsort Basel
Begutachtungsstatus Peer reviewed