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Elimination of P. Aeruginosa in mice by treatment with chlorine, and the use of microbiological and PCR analyses.

Scand. J. Lab. Anim. Sci. 36, 355-361 (2009)
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Unwanted micro-organisms in mice can jeopardize experimental protocols and should be eliminated if a colony becomes infected. The opportunistic bacterium Pseudomonas aeruginosa has been shown to cause infection in mice. In order to eliminate this bacterium from a specific-pathogen-free full barrier mouse area at our animal facility we treated mice with 7 ppm chlorine for 7 weeks and then with 10 ppm chlorine in the drinking water. The P. aeruginosa status of mice was examined by agar culture and PCR. The results show that 6 months after commencement of the treatment the colony was free of P. aeruginosa.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Pseudomonas-aerginosa; Cyxlophosphamide; Recommendations; Colonies; Samples
ISSN (print) / ISBN 0901-3393
Quellenangaben Band: 36, Heft: 4, Seiten: 355-361 Artikelnummer: , Supplement: ,
Verlag Scandinavian Federation for Laboratory Animal Science
Verlagsort Soborg, Denmark
Begutachtungsstatus Peer reviewed