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In vivo three-dimensional Raster Scan Optoacoustic Mesoscopy using Frequency Domain Inversion.

IEEE Trans. Med. Imaging 40, 3349-3357 (2021)
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Optoacoustic signals are typically reconstructed into images using inversion algorithms applied in the time-domain. However, time-domain reconstructions can be computationally intensive and therefore slow when large amounts of raw data are collected from an optoacoustic scan. Here we consider a fast weighted ω-κ (FWOK) algorithm operating in the frequency domain to accelerate the inversion in raster-scan optoacoustic mesoscopy (RSOM), while seamlessly incorporating impulse response correction with minimum computational burden. We investigate the FWOK performance with RSOM measurements from phantoms and mice in vivo and obtained 360-fold speed improvement over inversions based on the back-projection algorithm in the time-domain. This previously unexplored inversion of in vivo optoacoustic data with impulse response correction in frequency domain reconstructions points to a promising strategy of accelerating optoacoustic imaging computations, toward video-rate tomography.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Detectors ; Fast Fourier Transform ; Frequency-domain Analysis ; Image Reconstruction ; Imaging ; Mathematical Model ; Mesoscopy ; Omega-k Migration ; Optoacoustics ; Photoacoustics ; Time-domain Analysis ; Transducers ; Transfer Function; Reconstruction; Tomography; Microscopy
ISSN (print) / ISBN 0278-0062
e-ISSN 1558-254X
Quellenangaben Band: 40, Heft: 12, Seiten: 3349-3357 Artikelnummer: , Supplement: ,
Verlag Institute of Electrical and Electronics Engineers (IEEE)
Verlagsort New York, NY [u.a.]
Begutachtungsstatus Peer reviewed
Förderungen European Union
Bundesministerium fur Bildung und Forschung (BMBF), Bonn, Germany
Deutsche Forschungsgemeinschaft (DFG)