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Lafci, B.* ; Mercep, E. ; Herraiz, J.L.* ; Deán-Ben, X.L.* ; Razansky, D.

Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors.

Proc. SPIE 11642, DOI: 10.1117/12.2577907 (2021)
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Ultrasound (US) and optoacoustic (OA) imaging provide complementary information for quantitative analysis of the tumor microenvironment. Herein, we demonstrate the unique capabilities of transmission-reflection optoacoustic ultrasound (TROPUS) for characterizing breast cancer in tumor-bearing mice. For this, 4 different mice featuring orthotopic tumor of different sizes were scanned with a full-ring ultrasound transducer array to simultaneously render pulse-echo US images, speed of sound (SoS) maps and OA images. The tumor size, vascular density and its elastic parameters were further quantified in the images. Our results pave the way toward clinical translation of the hybrid TROPUS imaging for tumor detection and characterization.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Cancer Research ; Optoacoustic Imaging ; Photoacoustics ; Preclinical Imaging Of Tumors ; Speed Of Sound Imaging ; Ultrasound Computed Tomography
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Zeitschrift Proceedings of SPIE
Quellenangaben Band: 11642 Heft: , Seiten: , Artikelnummer: , Supplement: ,
Verlag SPIE
Begutachtungsstatus Peer reviewed
Förderungen Deutsche Forschungsgemeinschaft (DFG German Research Foundation) Germany's Excellence Strategy