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Wicker, T.* ; Mayer, K.F.X. ; Gundlach, H. ; Martis, M.M. ; Steuernagel, B.* ; Scholz, U.* ; Šimková, H.* ; Kubaláková, M.* ; Choulet, F.* ; Taudien, S.* ; Platzer, M.* ; Feuillet, C.* ; Fahima, T.* ; Budak, H.* ; Dolezel, J.* ; Keller, B.* ; Stein, N.*

Frequent gene movement and pseudogene evolution is common to the large and complex genomes of wheat, barley, and their relatives.

Plant Cell 23, 1706-1718 (2011)
Verlagsversion Volltext DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
All six arms of the group 1 chromosomes of hexaploid wheat (Triticum aestivum) were sequenced with Roche/454 to 1.3- to 2.2-fold coverage and compared with similar data sets from the homoeologous chromosome 1H of barley (Hordeum vulgare). Six to ten thousand gene sequences were sampled per chromosome. These were classified into genes that have their closest homologs in the Triticeae group 1 syntenic region in Brachypodium, rice (Oryza sativa), and/or sorghum (Sorghum bicolor) and genes that have their homologs elsewhere in these model grass genomes. Although the number of syntenic genes was similar between the homologous groups, the amount of nonsyntenic genes was found to be extremely diverse between wheat and barley and even between wheat subgenomes. Besides a small core group of genes that are nonsyntenic in other grasses but conserved among Triticeae, we found thousands of genic sequences that are specific to chromosomes of one single species or subgenome. By examining in detail 50 genes from chromosome 1H for which BAC sequences were available, we found that many represent pseudogenes that resulted from transposable element activity and double-strand break repair. Thus, Triticeae seem to accumulate nonsyntenic genes frequently. Since many of them are likely to be pseudogenes, total gene numbers in Triticeae are prone to pronounced overestimates.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter triticum-aestivum l.; nuclear-dna content; high-throughput; flow-cytometry; plant genomes; chromosome 1h; sequence; rice; transposons; grasses
ISSN (print) / ISBN 1040-4651
e-ISSN 1532-298X
Zeitschrift The Plant cell
Quellenangaben Band: 23, Heft: 5, Seiten: 1706-1718 Artikelnummer: , Supplement: ,
Verlag American Society of Plant Biologists (ASPB)
Begutachtungsstatus Peer reviewed