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Hölter, S.M. ; Wells, S.* ; Voikar, V.*

Improving biomedical research by automated behaviour monitoring in the animal home cage - action needed for networking.

Lab. Anim., DOI: 10.1177/00236772221117451 (2022)
Postprint DOI
Open Access Green
Licenced for HMGU: Verlagsversion online verfügbar 10/2025
The key goal in biomedical research is a better understanding of disease aetiologies, which ideally results in strategies and recommendations for the prevention of diseases before they arise, and in the development of effective therapies. However, many concerns have been expressed about the reproducibility and the translational validity of preclinical research in animal models to inform clinical trials in humans. It has been proposed that improving internal, external and construct validity of animal studies will lead to improved translatability. Automated behaviour monitoring in the animal's home cage, which allows for longitudinal assessment of individual trajectories over sufficiently long intervals for (chronic) drug treatment or phenotype progression, is a promising solution to these problems.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Home Cage Monitoring ; Cost Action ; Networking ; Three Rs
ISSN (print) / ISBN 0023-6772
e-ISSN 1758-1117
Zeitschrift Laboratory animals
Verlag Sage
Verlagsort London