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Long-term single-cell imaging of mammalian stem cells.

Nat. Methods 8, Suppl. S, S30-S35 (2011)
Verlagsversion DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Continuous long-term single-cell observation provides insight into the molecular control of cell fate. This is particularly important for rare and heterogeneous populations of cells, such as mammalian stem cells. The current lack of usable off-the-shelf hardware and software for such experiments makes their implementation technically challenging. Here I discuss the need for continuous single-cell quantification to understand molecular cell fate control as well as organizational and technical solutions for long-term imaging and tracking of stem cells.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter mouse cerebral-cortex; hematopoietic stem; in-vitro; progenitor cells; self-renewal; postnatal astroglia; systems biology; lineage choice; fate; generation
ISSN (print) / ISBN 1548-7091
e-ISSN 1548-7105
Zeitschrift Nature Methods
Quellenangaben Band: 8, Heft: 4, Seiten: S30-S35, Artikelnummer: , Supplement: Suppl. S
Verlag Nature Publishing Group
Verlagsort New York, NY
Begutachtungsstatus