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Yoo, H.* ; Kim, J.W.* ; Shishkov, M.* ; Namati, E.* ; Morse, T.* ; Shubochkin, R.* ; McCarthy, J.R.* ; Ntziachristos, V. ; Bouma, B.E.* ; Jaffer, F.A.* ; Tearney, G.J.*

Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo.

J. Nat. Med. 17, 1680-1684 (2011)
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Advancing understanding of human coronary artery disease requires new methods that can be used in patients for studying atherosclerotic plaque microstructure in relation to the molecular mechanisms that underlie its initiation, progression and clinical complications, including myocardial infarction and sudden cardiac death. Here we report a dual-modality intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo using a combination of optical frequency domain imaging (OFDI) and near-infrared fluorescence (NIRF) imaging. By providing simultaneous molecular information in the context of the surrounding tissue microstructure, this new catheter could provide new opportunities for investigating coronary atherosclerosis and stent healing and for identifying high-risk biological and structural coronary arterial plaques in vivo.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter no keywords
ISSN (print) / ISBN 1340-3443
e-ISSN 1861-0293
Quellenangaben Band: 17, Heft: 12, Seiten: 1680-1684 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort Tokyo [u.a.]
Begutachtungsstatus Peer reviewed