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Nat. Genet. 41, 280-282 (2009)
We present a three-stage analysis of genome-wide SNP data in 1,222 German individuals with myocardial infarction and 1,298 controls, in silico replication in three additional genome-wide datasets of coronary artery disease (CAD) and subsequent replication in similar to 25,000 subjects. We identified one new CAD risk locus on 3q22.3 in MRAS (P = 7.44 x 10(-13); OR = 1.15, 95% CI = 1.11-1.19), and suggestive association with a locus on 12q24.31 near HNF1A-C12orf43 (P = 4.81 x 10(-7); OR = 1.08, 95% CI = 1.05-1.11).
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Publication type Article: Journal article
Document type Scientific Article
Keywords association; genome
ISSN (print) / ISBN 1061-4036
Journal Nature Genetics
Quellenangaben Volume: 41, Issue: 3, Pages: 280-282
Publisher Nature Publishing Group
Publishing Place New York, NY
Reviewing status Peer reviewed