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DI-ICR-FT/MS-based high throughput deep metabotyping: A case study of the Caenorhabditis. elegans – Pseudomonas aeruginosa infection model

Titel Pressemitteilung:


Next Generation Metabotyping

Apr 2015 BGC
Prof. Dr. Philippe Schmitt-Kopplin PDF PR 2015-01-01
Core statement:

This study fullfilled two goals. The first was a detailed metabolomics study of Caenorhabditis. elegans – Pseudomonas aeruginosa infection model to understand interorganismic interactions on a molecular level. The second was a proof of principle that the technology of ICR-FT/MS is throughput compatible and delivered hundreds of organism specific compounds in limited time.

Core statement Pressemitteilung:

Neuherberg, January 14, 2015. In metabolomics there is an ever demanding growing need for more comprehensive and faster analysis methods to cope with the increasing size of biological studies. Scientists at the Helmholtz Zentrum München have shown that ultra-high resolution mass spectrometry can be used for detailed information on metabolic states. Their results have been published in the scientific journal ‚Analytical and Bioanalytical Chemistry’.

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