PuSH - Publication Server of Helmholtz Zentrum München

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Titel:

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes.


Titel Pressemitteilung:

Diabetes-Medikament beeinflusst Cholesterin-Werte

Diabetes drug modulates cholesterol levels

Oct 2015 EPI2
EPI
EH
G-504091-001
Dr. Rui Wang-Sattler PDF WB 2015-12-01
AR 2015-11-01
PR 2015-08-01
Publication
Core statement:

Our results indicate that metformin intake activates AMPK and consequently suppresses FADS, which leads to reduced levels of the three acyl-alkyl PCs and LDL-C. Our findings suggest potential beneficial effects of metformin in the prevention of cardiovascular disease. 


Core statement Pressemitteilung:

Neuherberg, August 6, 2015. Besides affecting the blood sugar levels, the substance Metformin, also has an impact on blood fat levels. This was elucidated by an interdisciplinary team of the German Center for Diabetes Research (DZD) headed by Dr. Rui Wang-Sattler of the Helmholtz Zentrum München. Especially the harmful LDL cholesterol can be reduced. The results have recently been published in the journal ‘Diabetes Care’.

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