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Abfrage Programm/Institut/Gruppe PSP-Element Kontakt Anhang Verwendung Publikation
Titel:

Hypergraphs and Cellular Networks

Oct 2009 IBIS
SAM
G-503700-001
Theis PDF
PM DE: PDF
PM EN: PDF
PR 2009-06-01
Publikation
Core statement:

Although hypergraphs occur ubiquitously in the context of biological network analysis, the notion of hypergraphs is known to a much lesser extent than that of graphs. Hypergraphs are generalization of graphs allowing one to model not only bilateral but also multilateral relationships in (biological) networks. In our contribution we (i) give an introduction to the notion of hypergraphs (ii) highlight the differences to graphs and illustrate that valuable information may be lost when simplifying hypergraphs to graphs (iii) review examples of using hypergraph theory in computational biology (iv) propose applications in computational biology in fields where graph analysis is predominantly used but where a hypergraph interpretation produces novel results e.g. in the context of a microRNA-protein interaction network.

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