Neue Zusammenhänge zwischen Genen und Stoffwechsel identifiziert

Atlas shows how genes affect our metabolism

In the most comprehensive exploration of the association between genetic variation and human metabolism, researchers have provided unprecedented insights into how genetic variants influence complex disease and drug response through metabolic pathways. The international team, including scientists of the Helmholtz Zentrum München, has linked 145 genetic regions with more than 400 molecules involved in human metabolism in human blood. This atlas of genetic associations with metabolism provides many new opportunities to understand the molecular pathways underlying associations with common, complex diseases.