A combined omics approach to generate the surface atlas of human naive CD4+ T cells during early TCR activation
Wissenschaftler kartieren Oberfläche von Immunzellen
Scientists map surface of immune cells
||Dr. Kathrin Suttner||
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The cell surface atlas of human naïve and activated CD4+ T cells provides novel potential immune targets usable for therapeutic treatments and also gives for the first time an extensive overview of the cell surface expression pattern of CD markers and surface molecules detected on these cells.
Core statement Pressemitteilung:
Neuherberg, Germany, 12th of June 2015. The immune system must constantly adapt to its environment in order to protect a body effectively. The so-called T cells are an important example in this regard. One of their functions is to form the immune system's "memory". Researchers at the Helmholtz Zentrum München and the Technische Universität München recently examined the surface of precursors of these T cells and identified previously unknown proteins there. According to the scientists, the results, which were published in the journal Molecular & Cellular Proteomics, could supply approaches to new therapies in the area of asthma and allergies.
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